Route 60 travels a zig-zag route through Broadway, First Hill, International District, Beacon Hill, Georgetown, and (on weekdays only) White Center. It runs every half hour on weekdays and weekends. Weekend service is more limited than on weekdays. It connects with many other bus routes. Forty-foot diesel buses are typically run on route 60.
Route 60 makes stops at The Poly Clinic, Swedish Hospital, Virginia Mason Hospital, Puget Sound Blood Center, Harborview Medical Center, and (on weekdays only) VA Medical Center.
Route 60 stops at Seattle Central Community College, Seattle University, and Cleveland High School.
Route 60 stops close to the Capitol Hill Library and the Beacon Hill Library.
Route 60 stops at Amazon.com headquarters. On weekdays, it also stops at Boeing Plant 2.